Artizen has 2 noise reduction filters,
Iterations and Bilateral with each having it's pros and cons. Below is a
screenshot of a mountain photo with a lot of noise in the sky, which
should be a consistent bluish tone instead has red and green pixel level
shifts. This type of noise is usually caused by setting the ISO option
on the camera too high or a scene is dark and taking a long exposure.
This is because digital cameras produce 3 types of noise, random ,
"fixed pattern", and banding. The example below shows random
noise and is usually the hardest to remove.

This is a before screen shot of an image (480% zoom) with
random noise
on the
mountain and in the sky. In addition to this, the noise is both in luminosity and color based.
Bilateral Noise Reduction
Bilateral Noise Reduction is a very
powerful fast way of removing random noise in a photo, but can suffer from
starting to get a blurry look if the values are set to high. The big
advantage of this method over the Iteration method is that can have a
larger area of influence and produce smoother results.
Radius = This option
determines the range of influence, and although this value can be set
rather high usually values between 1 - 4 is more than enough cause image
noise on the pixel level.
Threshold = This option
determines the amount of influence (which pixels will be affect) within
the range of influence determined by the Radius option. If this value was
set to the max but the Radius is 0 then nothing will change.
In this example you can see in this
photo that all the noise in the sky has been significantly been reduced.

Iteration Noise Reduction
Iteration Noise Reduction is micro
noise reduction filter which reduces noise in a small area of influence.
The advantage of this method over the Bilateral method is that it better
preserves micro detail that can be lost using the Bilateral method.
Iteration = This option controls the number of loops the function
will repeat to produce the final results. Increasing this value to high
could cause to much blurring depending on the image as well as taking
very long. A good initial value is usually 1 or 2. Range (1-10)
Sharpness = This option tries to restore lost detail in the image
so the higher the value the great the local sharpness. This variable
usually doesn't need a value great than 1, but that is optional. Range
(0-5)
Red, Green, Blue, Luminosity = These 4 options all control the
amount of correction that is applied to each channel. These options are
very soft and can be very hard to notice the changes in some images, so
working with a zoomed images is usually essential if changing these
values is required. The cleanest results are achieved when these value
are higher so 100% is usually the best choice. Range (0-100%)

Even though
this image has been reduced from it's original size it is clearly
visible that the many different colors in the sky have been reduced and
that the mountain has a more consistent tone.